TP53+Liver+Mutations

TP53 Mutations in Liver Cancer Tumor Samples
**Highest Frequency Mutation Details**  Highest frequency TP53 mutations in liver cancer tumor samples are all missense substitution mutations. These mutations occur on the center region of the gene.
 * = **Amino Acid Location** ||= **Amino Acid Mutation** ||= **Nucleotide Mutation** ||= **Mutation Type** ||= **Number of Samples** ||= **Frequency** ||
 * = p.157 ||= p.V157F ||= c.469 G>T ||= Missense Substitution ||= 23 ||= 3.03% ||
 * = p.175 ||= p.R175H ||= c.524 G>A ||= Missense Substitution ||= 9 ||= 1.19% ||
 * = p.220 ||= p.Y220C ||= c.659 A>G ||= Missense Substitution ||= 7 ||= .923% ||
 * = p.249 ||= p.R249S ||= c.747 G>T ||= Missense Substitution ||= 217 ||= 28.6% ||
 * = p.273 ||= p.R273C ||= c.817 C>T ||= Missense Substitution ||= 15 ||= 1.98% ||

 **Complete Mutation Spectrum**

The complete TP53 mutation spectrum in liver cancer tumor samples show that mutations mainly fall on the center region of the gene,  although there are a a few scattered mutations in the left and right regions of the gene.

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