CDKN2a+Liver+Mutations

CDKN2a Mutations in Liver Cancer Tumor Samples
**Highest Frequency Mutation Details**   Highest frequency CDKN2a mutations in liver cancer tumor samples are mainly deletion mutations where either the whole gene is deleted or a large segment of the gene is deleted. The missense substitutions fall on the right regions of the gene.
 * = **Amino Acid Location** ||= **Amino Acid Mutation** ||= **Nucleotide Mutation** ||= **Mutation Type** ||= **Number of Samples** ||= **Frequency** ||
 * = p.102 ||= p.A102E ||= c.305 C>A ||= Missense Substitution ||= 2 ||= 2.41% ||
 * = p.112 ||= p.R112G ||= c.334 C>G ||= Missense Substitution ||= 2 ||= 2.41% ||
 * = N/A ||= N/A ||= c.1_471 del 471 ||= Gene Deletion ||= 3 ||= 3.61% ||
 * = N/A ||= N/A ||= c.1_457 del 457 ||= Gene Deletion ||= 5 ||= 6.02% ||
 * = N/A ||= N/A ||= c.1_150 del 150 ||= Deletion ||= 3 ||= 3.61% ||
 * = N/A ||= N/A ||= 151_457 del 307 ||= Deletion ||= 44 ||= 53.0% ||

 **Complete Mutation Spectrum **

 The complete CDKN2a mutation spectrum in liver cancer tumor samples show the mutations that do not include the major deletions. Substitution and simple frameshift deletions occur throughout the segment of the gene.



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