CDKN2a+Lung+Mutations

CDKN2a Mutations in Lung Cancer Samples
**Highest Frequency Mutation Details**   Highest frequency CDKN2a mutations in lung cancer tumor samples are mainly deletion mutations, where either the whole gene is deleted or a large segment of the gene is deleted. The nonsense substitution mutation occurs on the center region of the gene.
 * = **Amino Acid Location** ||= **Amino Acid Mutation** ||= **Nucleotide Mutation** ||= **Mutation Type** ||= **Number of Samples** ||= **Frequency** ||
 * = p.69 ||= p.E69* ||= c.205 G>T ||= Nonsense Substitution ||= 8 ||= 2.71% ||
 * = N/A ||= N/A ||= c.1_471 del471 ||= Gene Deletion ||= 103 ||= 34.9% ||
 * = N/A ||= N/A ||= c.1_457 del457 ||= Gene Deletion ||= 42 ||= 14.2% ||
 * = N/A ||= N/A ||= c.1_150 del150 ||= Deletion ||= 22 ||= 7.46% ||
 * = N/A ||= N/A ||= c.151_457 del307 ||= Deletion ||= 7 ||= 2.37% ||

 **Complete Mutation Spectrum **

 The complete CDKN2a mutation spectrum in lung cancer tumor samples show the mutations that do not include the major deletions. Substitution and simple frameshift deletions and additions occur throughout the segment of the gene.

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