CDKN2a+CNS+mutations

CDKN2a Mutations in CNS Cancer Tumor Samples
**Highest Frequency Mutation Details** 

 Highest frequency CDKN2a mutations in CNS cancer tumor samples are mostly deletion mutations, where either the whole gene is deleted or a large portion of the gene is deleted.
 * = **Amino Acid Location** ||= **Amino Acid Mutation** ||= **Nucleotide Mutation** ||= **Mutation Type** ||= **Number of Samples** ||= **Frequency** ||
 * = p.83 ||= p.H83Y ||= c.247 C>T ||= Missense Substitution ||= 3 ||=  ||
 * = N/A ||= N/A ||= c.1_471 del 471 ||= Gene Deletion ||= 112 ||= 43.6% ||
 * = N/A ||= N/A ||= c.1_150 del 150 ||= Deletion ||= 46 ||= 17.9% ||
 * = N/A ||= N/A ||= c.1_457 del 457 ||= Deletion ||= 5 ||= 1.95% ||
 * = N/A ||= N/A ||= c.151_457 del 307 ||= Deletion ||= 67 ||= 26.1% ||

 **Complete Mutation Spectrum **

The complete CDKN2a mutation spectrum in CNS cancer tumor samples show the mutations that do not include large segment deletions. The substitution and simple frameshift mutations occur throughout the length of the gene, clustering mainly on the center-right and right regions.

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