Useful+Terminology

Clarification of terms used when describing and analyzing the relationship between p53 mutations, sunscreen, and skin cancer.


 * Carcinogenesis:** Creation of cancer; Process by which normal cells transform into cancer cells


 * C3H Mice:** “General purpose” mice strain used in a wide variety of research areas; more resistant to endotoxin due to a mutation in C3H/HeJ at the lipopolysaccharide response locus; more susceptible by infection by Gram-negative bacteria (i.e. Salmonella)


 * Edema:** Swelling cause by the buildup of fluid in the tissues


 * Erythema:** A “Sunburn”; the redness of skin or mucous membranes caused by increased bloodflow to the surface capillaries


 * Hyperplasia: I**ncreased cell production in a normal tissue or organ


 * Immunosuppression:** An act that reduces the activation or efficacy of the immune system


 * Irradiation:** Process by which an object is exposed to radiation (natural or unnatural sources)


 * PCR:** Technology used to amplify parts of DNA


 * Photoaging:** Changes in the skin’s character induced by chronic UVA and UVB exposure


 * Photocarcinogenesis:** The development of skin cancer from a collection of events as a result of UV radiation


 * Photoprotection:** Mechanisms that minimize the damage suffered by human cells after UV radiation exposure

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